From the best and most famous bounty hunter to the most wanted criminal on the planet, what a brutal twist of fate. In High on Life 2, the hunter becomes the hunted as your reputation flips overnight and the entire galaxy locks its eyes on you.
You now have to face and eliminate your fellow bounty hunters after learning the truth Lizzie uncovered. This is only the beginning of a much bigger storm.
So, if you want the full story and every detail, dive into our complete walkthrough of the game.
Table of contents
Prologue Walkthrough

Everything was finally calm. You were kicking back, enjoying life and soaking in the glory after clearing the G3 threat. That’s when all of a sudden, your peace shatters. A bounty pops up on the TV screen, and the target is your own sister, Lizzie.
As shock hits hard, questions start racing. Why is there a price on her head, and who would dare place it?
With no time to waste, you rush out to find her, and from that moment on, your world spins into a wild chain of events you never saw coming.
Get Briefed

You rescue Lizzie and uncover a dark secret that your fame and success kept hidden from view. Rhea Pharma is planning to trade illegally with people and exploit them to fuel its twisted drug operations.
The quiet life had already started to feel dull, so this is the perfect chance to get your blood pumping and your adrenaline surging as you dive headfirst into the chaos.
Kill Billionaire Larry Pinkstock

Before you can reach the CEO of Rhea Pharma, you need to hunt down a few targets first in hopes of uncovering leads about the man himself. Each trail points you closer, and every step raises the stakes.
Your first stop is billionaire Larry Pinkstock. He believes he is untouchable while cruising on his luxury ship. But you are about to storm his floating fortress and bring the fight straight to him.
Kill Senator Muppy Doo

Your next target is Senator Muppy Doo. He sees himself as untouchable, perched high in a tower of power where no one can challenge him or even bother him.
That sense of importance has pushed him to back the Rhea Pharma’s research, and as he struts across the HumanCon stage to deliver his speech. He has no idea that not only one, but two determined people are racing through the crowd to end him.
Pick Up Your Half-Brother Jeppy

After you take out both of the main bounties, your sister Lizzie has some family business for you to handle.
Your mom and Lezduit have a child, and now she needs you to go pick them up. You had no idea this was coming, but it’s time to go meet your half-brother Jeppy.
Dinner With Mom

Jeppy isn’t the only family member you need to deal with; your mom is also in town, and she wants to see her children and have a family dinner.
Technically, a peaceful family meal is out of the question since both of you are wanted criminals, but it’s your mom, so you’ve got to go and see her.
Kill Finance Wiz James Stevenson

Your third target is the Finance Wiz, James Stevenson. You have no clue what you’re dealing with since you don’t even know what he looks like.
The only lead you have is that he’s been spotted in the penthouse at Circuit Arcadia, and that’s it. So you follow this one lead, hoping it will get you to him.
Prison Escape

Three targets are down, and the team has decided to throw a party to change the pace from all the killing.
You’re in charge of grabbing some party supplies, but somehow end up in prison instead. What a turn of events.
Kill Movie Star Bronkin Bucko

Your fourth bounty target is the Movie Star Bronkin Bucko. He is a huge celebrity, so getting close to him could stir up some trouble.
But trust us, you will be very surprised at how this bounty unfolds. The game is just that good, keeping the excitement high every step of the way. We know you are already curious, so go ahead and hit the button below.
Kill Scientist Professor Berkel

The final target you need to track down is Scientist Professor Berkel, head of R&D and the mastermind behind all the experiments designed to turn humans into pills.
She appears to be investigating a strange anomaly near the Pinkstock shores, but you will be surprised by what she has gotten herself into.
Kill Rhea Pharma CEO

The climax has arrived in High on Life 2: every challenge you’ve faced, every bounty you’ve killed, has brought you to this decisive moment; confronting Nipulon, the CEO of Rhea Pharma.
Now it all comes down to the pivotal courtroom showdown, where Rhea Pharmaceuticals aims to legalize humans as consumable substances.
Your mission is clear: put an end to this plan, protect humanity, and erase the shadow of Rhea Pharma once and for all.
Thank you for reading this Into Indie Games walkthrough hub for High On Life 2.
More Guides On Into Indie Games
For more guides and walkthroughs, be sure to check out the links below:
Into Indie Games Homepage
High On Life 2 – Walkthrough Hub
High On Life 2 – Prologue Walkthrough
High On Life 2 – Get Briefed Walkthrough
High On Life 2 – Kill Billionaire Larry Pinkstock Walkthrough
Nioh 3 – Guides And Walkthrough Hub

Former Staff Writer at TheGamer, with over 1,000 published articles covering everything from major AAA titles like Call of Duty, Elden Ring, and Dragon’s Dogma 2 to trending indie games like Blasphemous, Palworld, and Kingdom Come: Deliverance 2, and many, many more titles!