Resident Evil Requiem has recently been released, and it broke the record for concurrent players of every single Resident Evil game on Steam. The reception has also been very positive. For more information, head over to its Steam page.
As this game emphasizes the survival horror aspect, you can expect some pretty tough encounters and challenging puzzles. In this guide, I will provide a complete walkthrough on how to find all of the quartz and escape the Care Center in Resident Evil Requiem. However, there is a twist, so you will not ultimately escape.
Table of contents
- Escape The Care Center – Find And Place The Quartz
- Exploring The West Wing
- Open The Door With The Red Jewel
- Exploring The East Wing
- Access The Areas Using The ID Wristband
- Head Back To The West Wing
- How To Unlock The Pantry
- Head Inside The Garage
- Head Back To The East Wing
- Head To the Isolation Ward
- Take The Kid To The Puzzle Box
- Get Emily Back
Escape The Care Center – Find And Place The Quartz

Your objective is now to escape the care center, and to do that, you need to complete the sun, moon, and star puzzle. You need to explore the east and west wing areas now. So, in order to do that, go ahead and enter the room to the right. Pass through both of these areas, and then you will see a door on the right.

Enter and save your game. There will also be storage that you can use to store your items. Store any item to unlock an achievement or trophy. Also, pick up the green herb and then enter the door with the red light above it. As you do, a cutscene will commence, and when it ends, you will have the West Wing Keycard.
Exploring The West Wing
Now that you have the keycard, head back and swipe it to enter the West Wing. Then head left, and along the path on the right side, you will see a door that requires something to be fitted inside for it to open. Follow the path and then enter through the door to your right.
Stealthily Escape The Monster

Ahead will be a monster minding its own business. I do not recommend using the Requiem here as it will not do much, and you only have one bullet. The best way is to crouch down and wait for him to go to the other side. Then wait for him to head to the cart, and when he is done, move the cart ahead.
When he says next, you should hide and wait for him to get busy again. Then move the cart while he is butchering, and then exit through the door on the left.
Note: Another method to do this is by luring the monster to the left side of the area where you came from and shooting it in the leg. You can also perform a melee attack. Shooting it in the leg will be enough, as that will give you enough time to escape through the door.
Escape From The Infected

Ahead will be an infected, so go past him and ahead on the right side, unlock the door for a shortcut. You can now go back and save your game. Then come back, and this time head right. Then go ahead a little and head right again. Inside the room on the right side, you will find a handgun. However, there will not be any bullets inside.
So head straight and enter through the door to the left. Go ahead and enter through another door to the left. Inside, you will find a makeshift knife and a couple of bullets. Now you can defeat the infected.
Shoot him twice, and if the melee prompt appears, press the button. That will not be enough to defeat him, so use the knife to finish the job, and the enemy will drop a hunting knife. Pick it up and then exit the room.

After that, go left, pick up the antique coin, go ahead, and break the box right next to the stairs to get some ammo. Then an infected will come down from the stairs. Take care of it, and after that, head left to rotate the valve wheel. It will break, so you now have to head up the stairs.
Head Up The Stairs To Continue Progressing

Head up the stairs, and you will find the map of the West Wing. Then head to the top to get a green herb and some ammo. After getting that, go back down and enter the area where you found the map. Head left to enter the bar and lounge area.

Note: Inside the area, you can also find another handgun and some ammo. However, you will have to defeat three enemies (you will get an antique coin by eliminating the infected woman in the white dress). Aside from that, there is a safe containing three antique coins. Simply move the dial to left 10, right 80, left 30, and you should be able to unlock the safe.
On the piano is an antique coin, so pick it up and then get out through the door to the right. Then go straight and enter from the left. Interact with the white coat to get a note. The note contains a hint. You will also find some ammo and a green herb inside the room.
Enter The Chairman’s Office To Get The Moon Quartz

So pick them up, get out, and enter the Chairman’s Office. On the left side, you will find the Unicorn Trinket Box. Pick it up and rotate it to find a switch on the back side. Then it will open, and you will get the red jewel.

After that, head to the opposite side and then to the right. You now have to solve a puzzle to get the moon quartz. If you want to solve the puzzle by yourself, then head inside the Chairman’s Office and loot everything. You will find a pencil, some ammo, and a note.

You need to use the pencil on something in the previous room where the puzzle is. If you cannot figure it out, then I will tell you how to solve it. The far right one is the moon, the middle one is the sun, and the left one is the star. So the correct pattern is moon, sun, star, moon. Then pick up the moon quartz.
Now head out of the Chairman’s Office, go right, follow the path, and put the moon quartz inside its slot.
Open The Door With The Red Jewel

Remember the door you saw in the West Wing that required something to be inserted for it to open? You can open it by using the red jewel. Inside, you will find another antique coin and some things that you can unlock using these coins. Then head north, and on the left side, you will find a severed hand.
The hand will have the East Wing Keycard. There is another coin on the right side, on top of the shelf, and a green herb on the left side of the severed hand. Also, on the northwestern side of the area, you can find a vase. Break the vase to get another antique coin and some ammo. The antique coin won’t be inside the vase; instead, it will be on the left side.
You should have enough coins to get something by inserting them. By this point, I had six.
Exploring The East Wing

Now that you have the East Wing Keycard, it is time to explore that area. Head toward the East Wing door and swipe the keycard to enter. As you enter, you will see Mr. Raccoon again. To its right side, there will be a drawer, but you need a key to unlock it.

So head to the left side, grab the Green Herb, and enter the room to your right. Inside, there will be a body directly in front of you and two infected. To the right, there will be a safe with the combination 30, 10, and 50. Go near the infected while crouching, and to the right, there will be an item called the Hemolytic Injector.
You can use this to stealthily take out one of the infected just ahead. Then take out the other one normally. After that, exit through the door on the right side of where you took out the zombie stealthily. Then head right and turn on the light along the way.
Analyze the Blood Specimen

Go ahead and open the first locker to find scrap, a crafting material. Then head right, and you will find a Blood Collector near the sink. You can use it to gather infected blood to craft useful items. There is infected blood in the room that you can collect. As you pick up the Blood Collector, you will receive the objective of analyzing the blood specimen.

To the right will be the Denatured Blood Specimen. Pick it up and analyze it in the machine right next to it. Once the analysis is completed, you will be able to craft handgun ammo and the Hemolytic Injector.
Now go out of the area and take the first left. As you move ahead, the Isolation Ward will be on the left, but you do not have the security key to unlock it. Head north while evading the enemies, then enter through the first door on your right. Go to the other side and open the door to unlock a shortcut.
Head Inside the Lead Researcher’s Office

After that, go back, take a right, and follow the path. Pick up the antique coin from the table, then go up the stairs. There will be two zombies at the top. Lure them down the stairs, then head back up and go inside the Lead Researcher’s Office. Pick up the lockpick from the table. You can use the lockpick to unlock the locked drawer at the entrance of the East Wing to get rare material. Then head right, open the door, and go inside.

There will be plenty of things to interact with, so examine all of them. Upon interacting with the padlock, your objective will be updated to destroying it. Now head out of the office and then go left. There you will find the Level 1 ID Wristband, which grants clearance to Level 1 areas. As soon as you get it, a monster called Chunk will appear, so immediately run away.
Destroy the Padlock to Get the Sun Quartz

If Chunk is still at his location, roam around the area for a while, and he will no longer be in that position. However, note that when you return, Chunk will now be roaming the East Wing. It does not seem like you can eliminate him just yet. I used two Hemolytic Injectors on Chunk, but they did not seem to be enough.
You will need to shoot it with requiem to finish it. After that, head to the blood lab to analyze the new specimen you received. Then unlock the door using the wristband, and inside you will find more items and another specimen.

Head to the Lead Researcher’s Office, but do not enter. Go right and enter the room on the north side. Inside, there will be some zombies. Eliminate them and pick up the Corrosive.

Corrosive can destroy the padlock, so head back there, and a cutscene will commence featuring Victor. When the cutscene is over, destroy the padlock and use the combination Star, Sun, Moon, and Sun to get the Sun Quartz. Alongside that, there will be a leather notebook that contains instructions on how to unlock the organ transport box. You will understand what this is about shortly.
Access The Areas Using The ID Wristband

Now head inside the room from where you unlocked the shortcut. Inside will be the Ward Office. Use the ID Wristband to unlock the door and then enter. Inside, you will find the Converged Blood Specimen, some handgun ammo, and scrap. There will also be a briefcase containing a bullet for the Requiem.
Head Back To The West Wing

Now, head back to the West Wing to collect some items. Go to the Filing Room, which you can access from the dining area. Inside the Filing Room, there is another room you can unlock using the wristband. Unlock it, collect the loot, and then it is time to unlock the pantry.
You may have noticed that there is a pantry, but it requires a key to unlock.
How To Unlock The Pantry

You can access the pantry from the kitchen, but it will be locked. To unlock it, you need to eliminate the butcher monster. You can do this by shooting him twice with the Requiem. Two clean shots will bring him down, and when he falls, the monster will drop the Pantry Key.

Use that key to enter the pantry, and inside you will find some loot. Now head out of the kitchen from where you entered, and to the right, there will be another door that you can unlock using the wristband. Do so, then head inside the Custodian’s Office. Inside, you will find some loot and a wrench, which can be used instead of the valve wheel.
Head Inside The Garage

You can also access the storage box in this room and save your game. After that, exit and head through the blue door. Continue forward, and you will find the Organ Transport Box, which you need for the body in the East Wing. Once you have picked it up, head back, and a zombie will smash through with a bulldozer.

To make it stop, shoot the zombie. The first shot will break the mirror, and the second shot will do the job. Once it is stopped, you will be able to crawl under it, so move quickly and then head right. Take all the loot and then exit the garage. Then head to Cold Storage and unlock the door using the wrench. Once it is unlocked, go inside, and you will obtain the artificial heart for the body.
That is pretty much everything you need from the West Wing. There are more rooms you can explore, so feel free to explore them and collect useful items.
Head Back To The East Wing

Now that you have the required items, head back to the East Wing where the body is located. There will be some more enemies inside, and you will need either a requiem bullet to take one of them out or a Hemolytic Injector. The one who is near the body can be taken out normally. After eliminating them, place the artificial heart inside the body. Now you need to open the Organ Transport Box. You already have the instructions on how to do so.

The first step is to turn the switch to Hand, then move the lever to the middle. After that, turn off the fifth switch and then the second switch. Then turn the knob to Auto, and the Organ Transport Box should unlock. Once you open it, you will find the Artificial Lungs inside.
Place them inside the body. The body will then resurrect, so eliminate the zombie and pick up the Level 2 ID Wristband.
Head To the Isolation Ward

Now that you have access to the Level 2 Wristband, you can head inside the Isolation Ward. For now, there will not be any enemies, so explore the area thoroughly and loot everything. As you explore, you will come across the Security Manager’s Office.
Enter the office, and you will find the puzzle to get the last quartz. There will also be some bullets. Interact with the book on the desk to figure out the pattern. Then interact with the puzzle, and a cutscene will commence. When the cutscene ends, you will receive the Level 3 ID Wristband.
Take The Kid To The Puzzle Box

Next, head to where the kid is and interact with the door. A cutscene will commence, and when it ends, you will have to carry the kid to the puzzle box. I recommend placing the kid on the sofa and taking care of the enemies first. Alternatively, you can eliminate the zombies before bringing her out.
Either way, take care of the enemies and then carry her to the puzzle box. As you approach the puzzle box, a cutscene will commence, and enemies will start entering the Isolation Ward. You will find ammo around the area, so avoid staying in one spot for too long.

Take care of the zombies and then enter the room. Emily will take out the Star Quartz, and that monster from before, the one that is afraid of light, will return. Your objective now will be to get Emily back.
Get Emily Back

Head to where the monster retreated and descend. A cutscene will commence, and you will then resume control as Leon. You already have three quartz by now, but you won’t be able to proceed until you find Emily. With that, the quest to escape the care center in Resident Evil Requiem will be over. The next section is long and will take place in the basement of the Care Center.
You can also read the following pages:
- Into Indie Games Homepage
- Norse: Oath Of Blood – Walkthrough Hub
- High On Life 2 – Walkthrough Hub
- Disciples: Domination – Walkthrough Hub
- Yakuza Kiwami 3 & Dark Ties – Walkthrough Hub
Obaid Ur Rehman is a lifelong gaming enthusiast with a deep passion for writing about video games. While he enjoys all genres, he specializes in RPGs and Soulslike titles. After tackling some of the toughest bosses, he often unwinds with a cozy game to relax. Outside of gaming, Obaid enjoys watching anime, bingeing TV series, or staying active at the gym.